Recent Submissions

  • Effect of polymer surface properties on the reversibility of attachment of pseudomonas aeruginosa in the early stages of biofilm developmen 

    Pasmore, M.; Todd, Paul W.; Pfiefer, Blaine; Rhodes, Michael; Bowman, Christopher N. (2002-01)
    Biofilm fouling is a common problem in industrial water and medical systems. Prevention of biofilm formation is often difficult because of the numerous potential attachment and adhesion mechanisms of bacteria, and therefore ...
  • Testing antimicrobials against biofilm bacteria 

    Hamilton, Martin A. (202-03)
    A continuous flow reactor system was developed to evaluate the efficacy of antimicrobial treatments against sulfate-reducing bacterial biofilms. An annular reactor operating at a nominal dilution rate of 0.5 h-1 was fed ...
  • Developmental regulation of microbial biofilms 

    Hall-Stoodley, Luanne; Stoodley, Paul (2002-06)
    Sophisticated molecular and microscopic methods used to study biofilm formation are rapidly broadening our understanding of surface-attached microbial communities in a wide variety of organisms. Regulatory mechanisms ...
  • Mucosal biofilm formation on middle-ear mucosa in the chinchilla model of otitis media 

    Ehrlich, Garth D.; Veeh, Richard Harold; Wang, Xue; Costerton, J. William; Hayes, Jay D.; Hu, Fen Z.; Daigle, Bernie J.; Ehrlich, Miles D.; Post, J. C. (2002-04)
    CONTEXT Chronic otitis media with effusion (OME) has long been considered to be a sterile inflammatory process. The previous application of molecular diagnostic technologies to OME suggests that viable bacteria are present ...
  • Biofilms as complex differentiated communities 

    Stoodley, Paul; Sauer, K.; Davies, David Gwilyn; Costerton, J. William (2002-10)
    Prokaryotic biofilms that predominate in a diverse range of ecosystems are often composed of highly structured multispecies communities. Within these communities metabolic activities are integrated, and developmental ...
  • Action of chlorhexidine digluconate against yeast and filamentous forms in an early-stage candida albicans biofilm 

    Suci, Peter A.; Tyler, Bonnie J. (2002-11)
    An in situ method for sensitive detection of differences in the action of chlorhexidine against subpopulations of cells in Candida albicans biofilms is described. Detection relies on monitoring the kinetics of propidium ...
  • The influence of fluid shear on the structure and material properties of sulphate-reducing bacterial biofilms 

    Dunsmore, B. C.; Jacobsen, A.; Hall-Stoodley, Luanne; Bass, C. J.; Lappin-Scott, H. M.; Stoodley, Paul (2002-12)
    Biofilms of sulphate-reducing Desulfovibrio sp. EX265 were grown in square section glass capillary flow cells under a range of fluid flow velocities from 0.01 to 0.4 m/s (wall shear stress, τw, from 0.027 to 1.0 N/m2). In ...
  • Antimicrobials and biofilms 

    Czechowski, M. H.; Stoodley, Paul (2002-12)
  • Action of glutaraldehyde and nitrite against sulfate-reducing bacterial biofilms 

    Gardner, Lawrence Robert; Stewart, Philip S. (2002-12)
    A continuous flow reactor system was developed to evaluate the efficacy of antimicrobial treatments against sulfate-reducing bacterial biofilms. An annular reactor operating at a nominal dilution rate of 0.5 h-1 was fed ...
  • Antimicrobial activity of a novel catheter lock solution 

    Shah, Chirag B.; Mittelman, M. W.; Costerton, J. William; Parenteau, Stephen; Pelak, Michael; Arsenault, Richard; Mermel, Leonard A. (2002-06)
    Intravascular catheter-associated bloodstream infections significantly increase rates of morbidity and hospital costs. Microbial colonization and development of biofilms, which are known to be recalcitrant to antibiotic ...
  • Temperature and wetland plant species effects on wastewater treatment and root-zone oxidation 

    Allen, Winthrop C.; Hook, Paul B.; Biederman, Joel A.; Stein, Otto R. (2002)
    Constructed wetlands are widely used for wastewater treatment, but there is little information on processes affecting their performance in cold climates, effects of plants on seasonal performance, or plant selection for ...
  • Biodegradation of chlorinated solvents in a water unsaturated topsoil 

    Borch, T.; Ambus, Per; Laturnus, Frank; Svensmark, Bo; Grøn, Christian (2003-04)
    In order to investigate topsoils as potential sinks for chlorinated solvents from the atmosphere, the degradation of trichloromethane (CHCl3), 1,1,1-trichloroethane (CH3CCl3), tetrachloromethane (CCl4), trichloroethene ...
  • Diffusion in biofilms 

    Stewart, Philip S. (2003-03)
    Much of what makes life in a microbial biofilm different from life in a free aqueous suspension can be explained by invoking the phenomenon of diffusion. This article discusses the profound influence of the physics of the ...
  • Biofilm material properties as related to shear-induced deformation and detachment phenomena 

    Stoodley, Paul; Cargo, R.; Rupp, C. J.; Wilson, Suzanne; Klapper, Isaac (2002-12)
    Biofilms of various Pseudomonas aeruginosa strains were grown in glass flow cells under laminar and turbulent flows. By relating the physical deformation of biofilms to variations in fluid shear, we found that the biofilms ...
  • Assessing technician effects when extracting quantities from microscope images 

    Webb, D.; Hamilton, Martin A.; Harkin, Gary; Lawrence, S.; Camper, Anne K.; Lewandowski, Zbigniew (2003-04)
    Consider an experiment where the response is based on an image; e.g., an image captured to a computer file by a digital camera mounted on a microscope. Suppose relevant quantitative measures are extracted from the images ...
  • Role of nutrient limitation and stationary-phase existence in klebsiella pneumoniae biofilm resistance to ampicillin and ciprofloxacin 

    Anderl, Jeff N.; Zahller, Jeff; Roe, Frank; Stewart, Philip S. (2003-04)
    Biofilms formed by Klebsiella pneumoniae resisted killing during prolonged exposure to ampicillin or ciprofloxacin even though these agents have been shown to penetrate bacterial aggregates. Bacteria dispersed from biofilms ...
  • Biofilm monitoring: a perfect solution in search of a problem 

    Lewandowski, Zbigniew; Beyenal, Haluk (2003)
    The main problem with monitoring biofilms is data interpretation. Biofilm heterogeneity causes monitored parameters to vary from location to location in the same biofilm, and it is difficult to assess to what extent these ...
  • Movement, replication, and emigration rates of individual bacteria in a biofilm 

    Rice, A. R.; Hamilton, Martin A.; Camper, Anne K. (2003-02)
    Single-cell behavior within a biofilm was observed over a period of several hours. The observations were converted into quantitative stochastic rules governing the behavior of individual cells within a biofilm. Such a ...
  • A computer investigation of chemically mediated detachment in bacterial biofilms 

    Hunt, Stephen Michael; Hamilton, Martin A.; Sears, J.; Harkin, Gary; Reno, Jason (2003-05)
    A three-dimensional computer model was used to evaluate the effect of chemically mediated detachment on biofilm development in a negligible-shear environment. The model, BacLAB, combines conventional diffusion-reaction ...
  • Rheology of biofilms 

    Winston, M.; Rupp, Cory J.; Vinogradov, A. M.; Towler, Brett William; Adams, Heather; Stoodley, Paul (2003)
    The paper describes an experimental study concerning the mechanical properties of bacterial biofilms formed from the early dental plaque colonizer Streptoccocus mutans and pond water biofilms. Experiments reported in this ...

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