van Erp, Paul B. G.Bloomer, GaryWilkinson, Royce A.Wiedenheft, Blake A.2016-05-262016-05-262015-06Van Erp, Paul BG, Gary Bloomer, Royce Wilkinson, and Blake Wiedenheft. “The History and Market Impact of CRISPR RNA-Guided Nucleases.” Current Opinion in Virology 12 (June 2015): 85–90. doi:10.1016/j.coviro.2015.03.011.1879-6257https://scholarworks.montana.edu/handle/1/9879The interface between viruses and their hosts’ are hot spots for biological and biotechnological innovation. Bacteria use restriction endonucleases to destroy invading DNA, and industry has exploited these enzymes for molecular cut-and-paste reactions that are central to many recombinant DNA technologies. Today, another class of nucleases central to adaptive immune systems that protect bacteria and archaea from invading viruses and plasmids are blazing a similar path from basic science to profound biomedical and industrial applications.You are free to: Share — copy and redistribute the material in any medium or format Adapt — remix, transform, and build upon the material for any purpose, even commercially. The licensor cannot revoke these freedoms as long as you follow the license terms. Under the following terms: Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.http://creativecommons.org/licenses/by/4.0/legalcodeArticle