Stewart, Philip S.Davison, William M.Steenbergen, J. N.2017-07-122017-07-122009-05Stewart PS, Davison WM, Steenbergen JN, "Daptomycin rapidly penetrates a Staphylococcus epidermidis biofilm," Antimicrob. Agents Chemother. 2009 53 (8):3505-35070066-4804https://scholarworks.montana.edu/handle/1/13240Fluorescently-tagged daptomycin accessed the interior of Staphylococcus epidermidis biofilm cell clusters within minutes. The diffusion coefficient of daptomycin in the biofilm was 28% of its value in pure water. Daptomycin activity against staphylococci embedded in biofilms is unlikely to be limited by penetration of the antibiotic into the biofilm.Article