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dc.contributor.authorFigueroa, L. O.
dc.contributor.authorPitts, Betsey
dc.contributor.authorUchida, M.
dc.contributor.authorRichards, Abigail M.
dc.date.accessioned2016-11-29T18:06:40Z
dc.date.available2016-11-29T18:06:40Z
dc.date.issued2016-01
dc.identifier.citationFigueroa LO, Pitts B, Uchida M, Richards AM, "Vesicle self-assembly of amphiphilic siderophores produced by bacterial isolates from Soap Lake, Washington," Can. J. Chem. 2016 94(1):35-43.en_US
dc.identifier.urihttps://scholarworks.montana.edu/xmlui/handle/1/12263
dc.description.abstractDue to the emergence of staphylococcal biofilm infections, the need for advanced antibiotics is crucial. The aim of this investigation was to evaluate the potency and penetration of telavancin against staphylococcal biofilms using two different biofilm models. Multiple staphylococcal strains, including meticillin-sensitive Staphylococcus aureus ATCC 29213, vancomycin-intermediate S. aureus ATCC 700787, heterogeneously vancomycin-intermediate S. aureus ATCC 700698 and meticillin-sensitive Staphylococcus epidermidis ATCC 12228, were grown and treated in drip-flow reactors to determine log reductions due to telavancin treatment. After 3 days of biofilm growth and 24 h of treatment, mean log reductions for telavancin ranged from 1.65 to 2.17 depending on the bacterial strain tested. Penetration was evaluated qualitatively using confocal scanning laser microscopy to image the infiltration of fluorescently labelled antibiotic into a staphylococcal biofilm grown in a flow cell. Fluorescently labelled telavancin rapidly penetrated the biofilms with no alteration in the biofilm structure.en_US
dc.titleVesicle self-assembly of amphiphilic siderophores produced by bacterial isolates from Soap Lake, Washingtonen_US
dc.typeArticleen_US
mus.citation.extentfirstpage35en_US
mus.citation.extentlastpage43en_US
mus.citation.issue1en_US
mus.citation.journaltitleCanadian Journal of Chemistryen_US
mus.citation.volume94en_US
mus.identifier.categoryChemical & Material Sciencesen_US
mus.identifier.categoryEngineering & Computer Scienceen_US
mus.identifier.categoryLife Sciences & Earth Sciencesen_US
mus.identifier.doi10.1139/cjc-2015-0173en_US
mus.relation.collegeCollege of Agricultureen_US
mus.relation.collegeCollege of Engineeringen_US
mus.relation.collegeCollege of Letters & Scienceen_US
mus.relation.departmentCell Biology & Neuroscience.en_US
mus.relation.departmentCenter for Biofilm Engineering.en_US
mus.relation.departmentChemical & Biological Engineering.en_US
mus.relation.departmentChemistry & Biochemistry.en_US
mus.relation.departmentMicrobiology & Immunology.en_US
mus.relation.universityMontana State University - Bozemanen_US
mus.relation.researchgroupCenter for Biofilm Engineering.en_US
mus.data.thumbpage3en_US


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