Show simple item record

dc.contributor.authorMann, Ethan E.
dc.contributor.authorMettetal, M. Ryan
dc.contributor.authorMay, Rhea M.
dc.contributor.authorDrinker, M. C.
dc.contributor.authorStevenson, B. C.
dc.contributor.authorBaiamonte, V. L.
dc.contributor.authorMarso, J. M.
dc.contributor.authorDannemiller, E. A.
dc.contributor.authorParker, Albert E.
dc.contributor.authorReddy, Shravanthi T.
dc.contributor.authorSande, M. K.
dc.identifier.citationMann EE, Mettetal MR, May RM,Drinker MC, Stevenson BC, Baiamonte VL, Marso JM, Dannemiller EA, Parker AE, Reddy ST, Sande MK, "Surface micropattern resists bacterial contamination transferred by healthcare practitioners," Journal of Microbiology & Experimentation, December 2014 1(5):00032.en_US
dc.description.abstractEnvironmental contamination contributes to an estimated 20-40% of all hospitalacquiredinfections (HAI). Infection control practices continue to improve, butmultipronged approaches are necessary to fully combat the diversity of nosocomialpathogens and emerging multidrug resistant organisms. The Sharkletâ„¢ micropattern,inspired from the microtopography of shark skin, was recently shown to significantlyreduce surface contamination but has not been evaluated in a clinical setting. Thefocus of this study was the transfer of bacteria onto micropatterned surfaces comparedto unpatterned surfaces in a clinical simulation environment involving healthcarepractitioners. Physician volunteers were recruited to participate in an emergencymedicine scenario involving a contact-precaution patient with an acute pulmonaryembolism. Prior to scenario initiation, Staphylococcus aureus was inoculated onto theleg of a simulation mannequin and fresh micropatterned and unpatterned surfacefilms were placed on a code cart, cardiac defibrillator shock button, and epinephrinemedication vial. Six physicians interacted with micropatterned surfaces and fivephysicians interacted with unpatterned surfaces in separate scenarios. Bacterial loadloss from the first contact location (control film over the femoral pulse) to subsequentunpatterned or micropatterned surface test locations was quantified as a log reduction(LR) for each surface type.The code cart, cardiac defibrillator button, and medication vial locations withmicropatterned surfaces resulted in LRs that were larger than the unpatternedLRs by 0.64 (p=0.146), 1.14 (p=0.023), and 0.58 (p=0.083) respectively for eachlocation. The geometric mean CFU/RODAC at the first control surface touched at thefemoral pulse pads ranged from 175-250 CFU/RODAC (95% confidence interval).Thus, the micropatterned LRs were consistently greater than the unpatterned LRs,substantiating the micropattern-dependent reduction of microorganism transfer.Principal component analysis showed that the LRs for the code cart and the cardiacdefibrillator button highly covaried. Thus, a single mean LR was calculated fromthese two locations for each surface type; 5.4 times more bacteria attached to theunpatterned surfaces compared to the micropatterned surfaces (p = 0.058). Thesimulated clinical scenario involving healthcare practitioners demonstrated that themicropatterned surface reduced the transfer of bacterial contamination based onthe larger LRs for the micropatterned surface compared to control surfaces. Furtherinvestigation in hospital rooms where patients are receiving care will ultimately revealthe capability of micropatterned surfaces to minimize the incidence of HAIs.en_US
dc.rightsCC BY 4.0en_US
dc.titleSurface micropattern resists bacterial contamination transferred by healthcare practitionersen_US
mus.citation.journaltitleJournal of Microbiology & Experimentationen_US
mus.identifier.categoryChemical & Material Sciencesen_US
mus.identifier.categoryEngineering & Computer Scienceen_US
mus.identifier.categoryHealth & Medical Sciencesen_US
mus.identifier.categoryLife Sciences & Earth Sciencesen_US
mus.relation.collegeCollege of Agricultureen_US
mus.relation.collegeCollege of Education, Health & Human Developmenten_US
mus.relation.collegeCollege of Engineeringen_US
mus.relation.collegeCollege of Letters & Scienceen_US
mus.relation.departmentCenter for Biofilm Engineering.en_US
mus.relation.departmentChemical & Biological Engineering.en_US
mus.relation.departmentCivil Engineering.en_US
mus.relation.departmentHealth & Human Development.en_US
mus.relation.departmentMicrobiology & Immunology.en_US
mus.relation.universityMontana State University - Bozemanen_US
mus.relation.researchgroupCenter for Biofilm Engineering.en_US

Files in this item


This item appears in the following Collection(s)

Show simple item record

CC BY 4.0
Except where otherwise noted, this item's license is described as CC BY 4.0

MSU uses DSpace software, copyright © 2002-2017  Duraspace. For library collections that are not accessible, we are committed to providing reasonable accommodations and timely access to users with disabilities. For assistance, please submit an accessibility request for library material.