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dc.contributor.authorRupp, Cory J.
dc.contributor.authorFux, C. A.
dc.contributor.authorStoodley, Paul
dc.date.accessioned2017-07-20T14:21:05Z
dc.date.available2017-07-20T14:21:05Z
dc.date.issued2005-04
dc.identifier.citationRupp CJ, Fux CA, Stoodley P, "Viscoelasticity of Staphylococcus aureus biofilms in response to fluid shear allows resistance to detachment and facilitates rolling migration," Appl Environ Microbiol, 2005 71(4):2175-2178en_US
dc.identifier.issn0099-2240
dc.identifier.urihttps://scholarworks.montana.edu/xmlui/handle/1/13354
dc.description.abstractStaphylococcus aureus is a leading cause of catheter-related bloodstream infections and endocarditis. Both involve (i) biofilm formation, (ii) exposure to fluid shear, and (iii) high rates of dissemination. We found that viscoelasticity allowed S. aureus biofilms to resist detachment due to increased fluid shear by deformation, while remaining attached to a surface. Further, we report that S. aureus microcolonies moved downstream by rolling along the lumen walls of a glass flow cell, driven by the flow of the overlying fluid. The rolling appeared to be controlled by viscoelastic tethers. This tethered rolling may be important for the surface colonization of medical devices by nonmotile bacteria.en_US
dc.titleViscoelasticity of Staphylococcus aureus biofilms in response to fluid shear allows resistance to detachment and facilitates rolling migrationen_US
dc.typeArticleen_US
mus.citation.extentfirstpage2175en_US
mus.citation.extentlastpage2178en_US
mus.citation.issue4en_US
mus.citation.journaltitleApplied and Environmental Microbiologyen_US
mus.citation.volume71en_US
mus.identifier.categoryEngineering & Computer Scienceen_US
mus.identifier.doi10.1128/aem.71.4.2175-2178.2005en_US
mus.relation.collegeCollege of Engineeringen_US
mus.relation.departmentCenter for Biofilm Engineering.en_US
mus.relation.departmentChemical & Biological Engineering.en_US
mus.relation.departmentChemical Engineering.en_US
mus.relation.universityMontana State University - Bozemanen_US
mus.relation.researchgroupCenter for Biofilm Engineering.en_US
mus.data.thumbpage2en_US
mus.contributor.orcidStoodley, Paul|0000-0001-6069-273Xen_US


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