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dc.contributor.authorFux, C. A.
dc.contributor.authorStoodley, Paul
dc.contributor.authorHall-Stoodley, Luanne
dc.contributor.authorCosterton, J. William
dc.identifier.citationFux, C.A., P. Stoodley, L. Hall-Stoodley and J.W. Costerton, "Bacterial biofilms: a diagnostic and therapeutic challenge," Expert Review of Anti-infective Therapy, 1(4):89-105 (2003).en_US
dc.description.abstractBacteria have traditionally been regarded as individual organisms growing in homogeneous planktonic populations. However, bacteria in natural environments usually form communities of surface-adherent organisms embedded in an extracellular matrix, called biofilms. Current antimicrobial strategies often fail to control bacteria in the biofilm mode of growth. Treatment failure is particularly frequent in association with intracorporeal or transcutaneous medical devices and compromised host immunity. The rising prevalence of these risk factors over the last decades has paralleled the increase in biofilm infections. This review discusses the shortcomings of current therapies against biofilms both in theory and with clinical examples. Biofilm characteristics are described with a focus on new diagnostic and therapeutic targets.en_US
dc.titleBacterial biofilms: a diagnostic and therapeutic challengeen_US
mus.citation.journaltitleExpert Review of Anti-infective Therapyen_US
mus.identifier.categoryEngineering & Computer Scienceen_US
mus.relation.collegeCollege of Engineeringen_US
mus.relation.departmentCenter for Biofilm Engineering.en_US
mus.relation.departmentChemical & Biological Engineering.en_US
mus.relation.departmentChemical Engineering.en_US
mus.relation.universityMontana State University - Bozemanen_US
mus.relation.researchgroupCenter for Biofilm Engineering.en_US
mus.contributor.orcidStoodley, Paul|0000-0001-6069-273Xen_US

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