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dc.contributor.authorStewart, Philip S.
dc.contributor.authorCosterton, J. William
dc.date.accessioned2017-08-21T21:36:24Z
dc.date.available2017-08-21T21:36:24Z
dc.date.issued2001-07
dc.identifier.citationStewart PS and Costerton JW, "Antibiotic resistance of bacteria in biofilms," Lancet, 14 July 2001 358(9276):135–138.en_US
dc.identifier.issn0140-6736
dc.identifier.urihttps://scholarworks.montana.edu/xmlui/handle/1/13570
dc.description.abstractBacteria that adhere to implanted medical devices or damaged tissue can encase themselves in a hydrated matrix of polysaccharide and protein, and form a slimy layer known as a biofilm. Antibiotic resistance of bacteria in the biofilm mode of growth contributes to the chronicity of infections such as those associated with implanted medical devices. The mechanisms of resistance in biofilms are different from the now familiar plasmids, transposons, and mutations that confer innate resistance to individual bacterial cells. In biofilms, resistance seems to depend on multicellular strategies. We summarize the features of biofilm infections, review emerging mechanisms of resistance, and discuss potential therapies.en_US
dc.titleAntibiotic resistance of bacteria in biofilmsen_US
dc.typeArticleen_US
mus.citation.extentfirstpage135en_US
mus.citation.extentlastpage138en_US
mus.citation.issue9276en_US
mus.citation.journaltitleLanceten_US
mus.citation.volume368en_US
mus.identifier.categoryEngineering & Computer Scienceen_US
mus.identifier.doi10.1016/s0140-6736(01)05321-1en_US
mus.relation.collegeCollege of Engineeringen_US
mus.relation.departmentCenter for Biofilm Engineering.en_US
mus.relation.departmentChemical & Biological Engineering.en_US
mus.relation.departmentChemical Engineering.en_US
mus.relation.universityMontana State University - Bozemanen_US
mus.relation.researchgroupCenter for Biofilm Engineering.en_US
mus.data.thumbpage2en_US


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