Understanding and controlling detrimental bioreactor biofilms
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Date
1991-01
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Abstract
Unintentional biofilm formation within a bioreactor can have serious detrimental effects on bioreactor performance. These range from the obvious (reduced heat-transfer efficiency, increased frictional resistances, and fouling of internal diagnostic probes) to the more subtle (atypical econiches, species- or strain-specific adhesion, and inaccurate estimates of culture stoichiometric and kinetic parameters.) Detection and control of unwanted biofilm formation in bioreactors are also considered.
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Bryers, J.D., "Understanding and Controlling Detrimental Bioreactor Biofilms," Trends in Biotechnology, 9(1):422-426 (1991).