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dc.contributor.authorStewart, Philip S.
dc.date.accessioned2018-02-12T19:13:20Z
dc.date.available2018-02-12T19:13:20Z
dc.date.issued1998-08
dc.identifier.citationStewart, P.S., “A Review of Experimental Measurements of Effective Diffusive Permeabilities and Effective Diffusion Coefficients in Biofilms,” Biotechnology and Bioengineering, 59(3):261-272 (1998).en_US
dc.identifier.issn0006-3592
dc.identifier.urihttps://scholarworks.montana.edu/xmlui/handle/1/14349
dc.description.abstractExperimental measurements of effective diffusive permeabilities and effective diffusion coefficients in biofilms are reviewed. Effective diffusive permeabilities, the parameter appropriate to the analysis of reaction-diffusion interactions, depend on solute type and biofilm density. Three categories of solute physical chemistry with distinct diffusive properties were distinguished by the present analysis. In order of descending mean relative effective diffusive permeability (De/Daq) these were inorganic anions or cations (0.56), nonpolar solutes with molecular weights of 44 or less (0.43), and organic solutes of molecular weight greater than 44 (0.29). Effective diffusive permeabilities decrease sharply with increasing biomass volume fraction suggesting a serial resistance model of diffusion in biofilms as proposed by Hinson and Kocher (1996). A conceptual model of biofilm structure is proposed in which each cell is surrounded by a restricted permeability envelope. Effective diffusion coefficients, which are appropriate to the analysis of transient penetration of nonreactive solutes, are generally similar to effective diffusive permeabilities in biofilms of similar composition. In three studies that examine diffusion of very large molecular weight solutes ( > 5000) in biofilms, the average ratio of the relative effective diffusion coefficient of the large solute to the relative effective diffusion coefficient of either sucrose or fluorescein was 0.64, 0.61, and 0.36. It is proposed that large solutes are effectively excluded from microbial cells, that small solutes partition into and diffuse within cells, and that ionic solutes are excluded from cells but exhibit increased diffusive permeability (but decreased effective diffusion coefficients) due to sorption to the biofilm matrix. © 1998 John Wiley & Sons, Inc. Biotechnol Bioeng 59:261–272, 1998.en_US
dc.titleA review of experimental measurements of effective diffusive permeabilities and effective diffusion coefficients in biofilmsen_US
dc.typeArticleen_US
mus.citation.extentfirstpage261en_US
mus.citation.extentlastpage272en_US
mus.citation.issue3en_US
mus.citation.journaltitleBiotechnology and Bioengineeringen_US
mus.citation.volume59en_US
mus.identifier.categoryEngineering & Computer Scienceen_US
mus.identifier.doi10.1002/(sici)1097-0290(19980805)59:3<261::aid-bit1>3.0.co;2-9en_US
mus.relation.collegeCollege of Engineeringen_US
mus.relation.departmentCenter for Biofilm Engineering.en_US
mus.relation.departmentChemical & Biological Engineering.en_US
mus.relation.departmentChemical Engineering.en_US
mus.relation.universityMontana State University - Bozemanen_US
mus.relation.researchgroupCenter for Biofilm Engineering.en_US
mus.data.thumbpage7en_US
mus.contributor.orcidStewart, Philip S.|0000-0001-7773-8570en_US


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