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dc.contributor.authorParker, Albert E.
dc.contributor.authorHamilton, Martin A.
dc.contributor.authorGoeres, Darla M.
dc.date.accessioned2018-11-05T21:52:48Z
dc.date.available2018-11-05T21:52:48Z
dc.date.issued2018-08
dc.identifier.citationParker, Albert E., Martin A. Hamilton, and Darla M. Goeres. “Reproducibility of Antimicrobial Test Methods.” Scientific Reports 8, no. 1 (August 22, 2018). doi:10.1038/s41598-018-30282-3.en_US
dc.identifier.issn2045-2322
dc.identifier.urihttps://scholarworks.montana.edu/xmlui/handle/1/14991
dc.description.abstractWe review reproducibility results for methods that test antimicrobial efficacy against biofilms, spores and bacteria dried onto a surface. Our review, that included test results for Pseudomonas aeruginosa, Salmonella choleraesuis and Bacillus subtilis, suggests that the level of reproducibility depends on the efficacy of the antimicrobial agent being tested for each microbe and microbial environment. To determine the reproducibility of a method, several laboratories must independently test the same antimicrobial agent using the method. Little variability among the efficacy results suggests good reproducibility. Such reproducibility assessments currently are hampered by the absence of an objective process for deciding whether the variability is sufficiently small. We present a quantitative decision process that objectively determines whether any method that assesses antimicrobial efficacy is reproducible. Because the perception of acceptable reproducibility may differ among stakeholders, the decision process is governed by a stakeholder's specifications that necessarily includes the efficacy of the agents to be tested.en_US
dc.language.isoenen_US
dc.rightsCC BY, This license lets you distribute, remix, tweak, and build upon this work, even commercially, as long as you credit the original creator for this work. This is the most accommodating of licenses offered. Recommended for maximum dissemination and use of licensed materials.en_US
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/legalcodeen_US
dc.titleReproducibility of antimicrobial test methodsen_US
dc.typeArticleen_US
mus.citation.extentfirstpage12531en_US
mus.citation.issue1en_US
mus.citation.journaltitleScientific Reportsen_US
mus.citation.volume8en_US
mus.identifier.categoryEngineering & Computer Scienceen_US
mus.identifier.doi10.1038/s41598-018-30282-3en_US
mus.relation.collegeCollege of Engineeringen_US
mus.relation.departmentCenter for Biofilm Engineering.en_US
mus.relation.universityMontana State University - Bozemanen_US
mus.data.thumbpage5en_US


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CC BY, This license lets you distribute, remix, tweak, and build upon this work, even commercially, as long as you credit the original creator for this work. This is the most accommodating of licenses offered. Recommended for maximum dissemination and use of licensed materials.
Except where otherwise noted, this item's license is described as CC BY, This license lets you distribute, remix, tweak, and build upon this work, even commercially, as long as you credit the original creator for this work. This is the most accommodating of licenses offered. Recommended for maximum dissemination and use of licensed materials.

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