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dc.contributor.authorFlenniken, Michelle L.
dc.date.accessioned2019-04-03T18:34:38Z
dc.date.available2019-04-03T18:34:38Z
dc.date.issued2018-08
dc.identifier.citationFlenniken, Michelle L.. "Antiviral Defense in Invertebrates." Viruses 18, no. 8 (July 2018): 403-405. DOI:10.3390/v10080403.en_US
dc.identifier.issn1999-4915
dc.identifier.urihttps://scholarworks.montana.edu/xmlui/handle/1/15397
dc.description.abstractInvertebrate organisms include vectors of human viruses (mosquitoes, sand flies), model organisms (fruit fly), insect pollinators (honey bees and bumble bees), plant virus vectors (aphids), and commercially valuable aquatic species (oysters and shrimp) that play important roles in shaping ecosystems throughout the world. Like all organisms, invertebrates are infected by viruses and have, in turn, evolved strategies to limit virus infection. There are some fundamental similarities in host defense mechanisms, including the host recognition of non-self, pathogen-associated molecular patterns (e.g., viral dsRNA) that in turn stimulate the activation of host proteins, and expression of genes required to restrict virus replication, as well as unique aspects of specific host–virus interactions that are a result of co-evolution. Invertebrate antiviral defense mechanisms include canonical immune signaling cascades (e.g., Jak/STAT, Toll, Imd), heat shock responses, apoptosis, and dsRNA-triggered responses including the sequence-specific RNA interference mechanism and a less well characterized, non-sequence-specific dsRNA mediated response.en_US
dc.language.isoenen_US
dc.rightsCC BY: This license lets you distribute, remix, tweak, and build upon this work, even commercially, as long as you credit the original creator for this work. This is the most accommodating of licenses offered. Recommended for maximum dissemination and useen_US
dc.rights.urihttps://creativecommons.org/licenses/by/4.0/legalcodeen_US
dc.titleAntiviral Defense in Invertebratesen_US
dc.typeArticleen_US
mus.citation.extentfirstpage403en_US
mus.citation.issue8en_US
mus.citation.journaltitleVirusesen_US
mus.citation.volume10en_US
mus.identifier.categoryLife Sciences & Earth Sciencesen_US
mus.identifier.doi10.3390/v10080403en_US
mus.relation.collegeCollege of Agricultureen_US
mus.relation.departmentPlant Sciences & Plant Pathology.en_US
mus.relation.universityMontana State University - Bozemanen_US
mus.data.thumbpage1en_US
mus.contributor.orcidFlenniken, Michelle L.|0000-0003-0356-3370en_US


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CC BY: This license lets you distribute, remix, tweak, and build upon this work, even commercially, as long as you credit the original creator for this work. This is the most accommodating of licenses offered. Recommended for maximum dissemination and use
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