Based at Montana State University, the Center for American Indian and Rural Health Equity (CAIRHE) (“Care”) is an official state of Montana research center designated by the Montana University System Board of Regents. CAIRHE's mission is to reduce significant health disparities in Native and rural communities through community-based participatory research (CBPR) that is considerate of and consistent with their cultural beliefs. CAIRHE serves the people of Montana as a robust, interdisciplinary research center with strong engagement in communities across the state. Using proven CBPR methods, the Center and its investigators conduct groundbreaking health equity research and interventions that make a profound, sustainable difference in the lives of Montanans. CAIRHE also maintains a growing statewide and national network of research partners, the Health Equity Network, including clinical organizations, public health agencies, foundations, and other centers, as a way to expand collaboration and dissemination of positive research outcomes.