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dc.contributor.authorBrahmachary, Priyanka
dc.contributor.authorWelhaven, Hope D.
dc.contributor.authorJune, Ronald K.
dc.identifier.citationBrahmachary, P.P., Welhaven, H.D., June, R.K. (2023). Metabolomic Profiling to Understand Chondrocyte Metabolism. In: Stoddart, M.J., Della Bella, E., Armiento, A.R. (eds) Cartilage Tissue Engineering. Methods in Molecular Biology, vol 2598. Humana, New York, NY.
dc.description© 2023 The Author(s), under exclusive license to Springer Science+Business Media, LLC, part of Springer Natureen_US
dc.description.abstractMetabolism has long been recognized as a critical physiological process necessary to maintain homeostasis in all types of cells including the chondrocytes of articular cartilage. Alterations in metabolism in disease and metabolic adaptation to physiological stimuli such as mechanical loading are increasingly recognized as important for understanding musculoskeletal systems such as synovial joints. Metabolomics is an emerging technique that allows quantitative measurement of thousands of small molecule metabolites that serve as both products and reactants to myriad reactions of cellular biochemistry. This protocol describes procedures to perform metabolomic profiling on chondrocytes and other tissues and fluids within the synovial joint.en_US
dc.publisherSpringer Natureen_US
dc.rightscopyright Springer Nature 2022en_US
dc.subjectmetabolomic profilingen_US
dc.subjectmetabolite extractionen_US
dc.subjectsynovial fluidosteoarthritisen_US
dc.titleMetabolomic Profiling to Understand Chondrocyte Metabolismen_US
dc.typeBook chapteren_US
mus.relation.collegeCollege of Engineeringen_US
mus.relation.departmentMechanical & Industrial Engineering.en_US
mus.relation.universityMontana State University - Bozemanen_US
mus.citation.booktitleCartilage Tissue Engineeringen_US

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