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dc.contributor.authorMiles, Mary
dc.contributor.authorLeach, S.K.
dc.contributor.authorKraemer, W.J.
dc.contributor.authorDohi, K.
dc.contributor.authorBush, J.A.
dc.contributor.authorMastro, A.M.
dc.identifier.citationMiles MP, SK Leach, WJ Kraemer, K Dohi, JA Bush, and AM Mastro. Leukocyte adhesion molecule expression during intense resistance exercise. Journal of Applied Physiology 84(5):1604-9, 1998.en_US
dc.description.abstractWe hypothesized that expression of L-selectin and very late antigen-4 (VLA-4) integrin adhesion molecules would influence cell type-specific redistribution during exercise. Women subjects performed six sets of 10-repetition maximum squats. L-selectin and VLA-4 integrin were measured by using flow cytometry pre- and postexercise on peripheral blood neutrophils and lymphocytes (n 5 29 subjects) and lymphocyte subsets (n 5 70 subjects), respectively. Neutrophil concentration increased 41.8% (P , 0.001), whereas the percent expressing L-selectin was unchanged (79%). Lymphocyte concentration increased 61.8% (P , 0.001). The percent of T cells expressing L-selectin decreased from 73.5 6 8.9 to 68.2 6 11.4% (P , 0.001); the combined population of natural killer and B cells expressing L-selectin decreased from 80.4 6 22.5 to 62.7 6 25.8% (P , 0.001). VLA-4 integrin was expressed by nearly all lymphocytes both pre- and postexercise. The proportional decrease in L-selectin positive cells could have resulted from 1) shedding of L-selectin, 2) selective entry of L-selectin-negative subsets, or 3) selective removal of L-selectin-positive subsets.en_US
dc.publisherAmerican Physiological Societyen_US
dc.subjectHealth sciencesen_US
dc.titleLeukocyte Adhesion Molecule Expression During Intense Resistance Exerciseen_US
mus.citation.journaltitleJournal of Applied Physiology
mus.identifier.categoryHealth & Medical Sciences
mus.relation.collegeCollege of Education, Health & Human Development
mus.relation.collegeCollege of Education, Health & Human Development
mus.relation.departmentHealth & Human Development.en_US
mus.relation.universityMontana State University - Bozemanen_US

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