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dc.contributor.authorMiles, Mary
dc.contributor.authorDepner, Chris M.
dc.contributor.authorKirwan, Rochelle D.
dc.contributor.authorFrederickson, Sara J.
dc.date.accessioned2014-09-30T18:57:22Z
dc.date.available2014-09-30T18:57:22Z
dc.date.issued2010-08
dc.identifier.citationDepner CM, RD Kirwan, SJ Frederickson, and MP Miles. Enhanced inflammation with high carbohydrate intake during recovery from eccentric exercise. European Journal of Applied Physiology, 109(6):1067-1076, 2010.en_US
dc.identifier.issn1439-6319
dc.identifier.urihttp://dx.doi.org/10.1007/s00421-010-1448-0
dc.identifier.urihttps://scholarworks.montana.edu/xmlui/handle/1/3606
dc.description.abstractInflammation associated with adipose tissue is modulated by macronutrient availability. For example, glucose increases inflammation in obese but not lean individuals. Little is known about how macronutrient intake influences inflammation associated with muscle. The aim of this study was to determine the impact of macronutrient intake differences during recovery from eccentric exercise on the inflammatory response. The study was a cross-over design in which young men and women (n = 12) completed high and low carbohydrate (CHO) conditions. Both conditions consisted of six sets of ten maximal high-force eccentric contractions of the elbow flexors and extensors followed by a controlled diet for the first 8 h post-exercise. Glucose, insulin, tumor necrosis factor-α, interleukin (IL)-1β, IL-6, and C-reactive protein were measured from blood samples pre-exercise, 1.5, 4, 8, and 24 h post-exercise. Perceived muscle soreness, strength loss, and serum CK activity were measured through 120 h post-exercise. Perceived soreness was elevated (P < 0.001) at all time points post-exercise in both conditions and was higher (P < 0.05) in the high compared to the low CHO condition. IL-1β increased (P = 0.05) 24 h post-exercise in the high compared to the low CHO condition. There was a trend (P = 0.06) for IL-6 to be elevated in the high compared to the low CHO condition. We conclude that inflammation induced by high-force eccentric exercise in skeletal muscle is greater when a high CHO compared to a low CHO diet is consumed during recovery.en_US
dc.description.sponsorshipThis study was funded by the Department of Health and Human Development at Montana State University and an ADVANCE Leadership grant from the National Science Foundation.en_US
dc.publisherSpringeren_US
dc.subjectHealth sciencesen_US
dc.titleEnhanced inflammation with high carbohydrate intake during recovery from eccentric exerciseen_US
dc.typeArticleen_US
mus.citation.extentfirstpage1067en_US
mus.citation.extentlastpage1076en_US
mus.citation.issue6en_US
mus.citation.journaltitleEuropean Journal of Applied Physiologyen_US
mus.citation.volume109en_US
mus.identifier.categoryHealth & Medical Sciencesen_US
mus.identifier.doi10.1007/s00421-010-1448-0en_US
mus.relation.collegeCollege of Education, Health & Human Developmenten_US
mus.relation.collegeCollege of Education, Health & Human Development
mus.relation.departmentHealth & Human Development.en_US
mus.relation.universityMontana State University - Bozemanen_US


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