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dc.contributor.advisorCloninger, Mary
dc.contributor.authorBernhard, Samuel
dc.descriptionAbstract Onlyen_US
dc.description.abstractIn order to better understand the binding characteristics between lactose functionalized PAMAM dendrimers and the galactoside lectin Galectin-3, the synthetic production of heterogeneously functionalized TEMPO and Lactose PAMAM dendrimers were undertaken. To analyze the relevant lectin/ carbohydrate relationship, these dendrimers will be subjected to electron pair repulsion (EPR) studies. The implication of analyzing several dendrimer generations through EPR is that a quantitative understanding of the relationship between dendrimer size/ degree of functionalization and binding strength can be determined. In terms of progress, a significant portion of the synthesis has been completed. Optimized yields have been determined and characterization has been completed on the reactions that lead to the production of the Lactose tether.en_US
dc.titleAnalysis of GAL3 and Lactose functionalized PAMAM Binding by EPRen_US
mus.citation.conferenceMSU Student Research Celebration 2012
mus.relation.collegeCollege of Letters & Science
mus.relation.departmentChemistry & Biochemistry.en_US
mus.relation.universityMontana State University - Bozemanen_US

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