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dc.contributor.authorReijo Pera, Renee A.
dc.contributor.authorBriggs, Sharon F.
dc.identifier.citationBriggs, Sharon F, and Renee A Reijo Pera. “X Chromosome Inactivation: Recent Advances and a Look Forward.� Current Opinion in Genetics & Development 28 (October 2014): 78–82.en_US
dc.description.abstractX chromosome inactivation, the transcriptional inactivation of one X chromosome in somatic cells of female mammals, has revealed important advances in our understanding of development, epigenetic control, and RNA biology. Most of this knowledge comes from extensive studies in the mouse; however, there are some significant differences when compared to human biology. This is especially true in pluripotent cell types and, over the past few years, a significant amount of work has been dedicated to understanding these differences. This review focuses specifically on recent advances in the mechanism of Xist spreading, the role of Xist in cancer, the effects of reprogramming on X chromosome inactivation in human induced pluripotent stem cells, and new tools for studying X chromosome inactivation.en_US
dc.description.sponsorshipResearch funded by NIH/NHGRI (T32 HG000044, U01-HL100397)en_US
dc.subjectCellular biologyen_US
dc.titleX chromosome inactivation: recent advances and a look forwarden_US
mus.citation.journaltitleCurrent Opinion in Genetics & Developmenten_US
mus.identifier.categoryLife Sciences & Earth Sciencesen_US
mus.relation.collegeCollege of Letters & Science
mus.relation.collegeCollege of Letters & Sciencesen_US
mus.relation.departmentCell Biology & Neuroscience.en_US
mus.relation.universityMontana State University - Bozemanen_US
mus.contributor.orcidReijo Pera, Renee A.|0000-0002-6487-1329en_US

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