Center for Biofilm Engineering (CBE)
At the Center for Biofilm Engineering (CBE), multidisciplinary research teams develop beneficial uses for microbial biofilms and find solutions to industrially relevant biofilm problems. The CBE was established at Montana State University, Bozeman, in 1990 as a National Science Foundation Engineering Research Center. As part of the MSU College of Engineering, the CBE gives students a chance to get a head start on their careers by working on research teams led by world-recognized leaders in the biofilm field.
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Recent Submissions
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Open-source pneumatic pressure pump for drop-based microfluidic flow controls
(IOP Publishing, 2023-07)An open-source pneumatic pressure pump is engineered for driving fluid flow in a microfluidic device. It is designed to be a cost-effective and customizable alternative to commercial systems. The pneumatic pressure pump ... -
Harvesting and Disaggregation: An Overlooked Step in Biofilm Methods Research
(MyJove Corporation, 2022-04)Biofilm methods consist of four distinct steps: growing the biofilm in a relevant model, treating the mature biofilm, harvesting the biofilm from the surface and disaggregating the clumps, and analyzing the sample. Of the ... -
Bacterial transfer and biofilm formation in needleless connectors in a clinically simulated in vitro catheter model
(Cambridge University Press, 2023-04)Objective: Although needleless connectors (NCs) are widely used in clinical practice, they carry significant risk of bloodstream infection (BSI). In this study, we quantified differences in bacterial transfer and biofilm ... -
Culexarchaeia, a novel archaeal class of anaerobic generalists inhabiting geothermal environments
(Springer Science and Business Media LLC, 2022-09)Geothermal environments, including terrestrial hot springs and deep-sea hydrothermal sediments, often contain many poorly understood lineages of archaea. Here, we recovered ten metagenome-assembled genomes (MAGs) from ... -
Harvesting and Disaggregation: An Overlooked Step in Biofilm Methods Research
(MyJove Corporation, 2022-04)Biofilm methods consist of four distinct steps: growing the biofilm in a relevant model, treating the mature biofilm, harvesting the biofilm from the surface and disaggregating the clumps, and analyzing the sample. Of the ... -
Symmetry-Breaking Bifurcations of the Information Bottleneck and Related Problems
(MDPI AG, 2022-09)In this paper, we investigate the bifurcations of solutions to a class of degenerate constrained optimization problems. This study was motivated by the Information Bottleneck and Information Distortion problems, which have ... -
The Effect of a Prospective Intervention Program with Automated Monitoring on Hand Hygiene Performance in Long-term and Acute Care Units at a Veteran Affairs Medical Center
(Oxford University Press, 2022-12)Background. There is emerging evidence that implementation of an automated hand hygiene monitoring system (AHHMS) must be part of a multimodal hand hygiene (HH) program that includes complementary strategies. There are few ... -
Chickensplash! Exploring the health concerns of washing raw chicken
(AIP Publishing, 2022-03)The Food and Drug Administration recommends against washing raw chicken due to the risk of transferring dangerous food-borne pathogens through splashed drops of water. Many cooks continue to wash raw chicken despite this ... -
Anti-Biofilm Efficacy of Commonly Used Wound Care Products in In Vitro Settings
(MDPI AG, 2023-03)Considering the prevalence and pathogenicity of biofilms in wounds, this study was designed to evaluate the anti-biofilm capabilities of eight commercially available wound care products using established in vitro assays ... -
Calculating the limit of detection for a dilution series
(Elsevier BV, 2023-05)Aims. Microbial samples are often serially diluted to estimate the number of microbes in a sample, whether as colony-forming units of bacteria or algae, plaque forming units of viruses, or cells under a microscope. There ... -
Algal amendment enhances biogenic methane production from coals of different thermal maturity
(Frontiers Media SA, 2023-03)The addition of small amounts of algal biomass to stimulate methane production in coal seams is a promising low carbon renewable coalbed methane enhancement technique. However, little is known about how the addition of ... -
A global perspective on bacterial diversity in the terrestrial deep subsurface
(2023-01)While recent efforts to catalogue Earth’s microbial diversity have focused upon surface and marine habitats, 12–20 % of Earth’s biomass is suggested to exist in the terrestrial deep subsurface, compared to ~1.8 % in the ... -
Single-Cell Infection of Influenza A Virus Using Drop-Based Microfluidics
(American Society for Microbiology, 2022-10)Drop-based microfluidics has revolutionized single-cell studies and can be applied toward analyzing tens of thousands to millions of single cells and their products contained within picoliter-sized drops. Drop-based ... -
Hand hygiene product use by food employees in casual dining and quick-service restaurants
(Elsevier BV, 2023-02)Hand hygiene product usage characteristics by food employees when hand sanitizers are made available are not well understood. To investigate hand hygiene product usage in casual dining and quick-service restaurants, we ... -
Mitigation and use of biofilms in space for the benefit of human space exploration
(Elsevier BV, 2023-12)Biofilms are self-organized communities of microorganisms that are encased in an extracellular polymeric matrix and often found attached to surfaces. Biofilms are widely present on Earth, often found in diverse and sometimes ... -
The biofilm life cycle: expanding the conceptual model of biofilm formation
(Springer Science and Business Media LLC, 2022-10)Bacterial biofilms are often defined as communities of surface-attached bacteria and are typically depicted with a classic mushroom-shaped structure characteristic of Pseudomonas aeruginosa. However, it has become evident ... -
Imaging and plate counting to quantify the effect of an antimicrobial: A case study of a photo-activated chlorine dioxide treatment
(Oxford University Press, 2022-12)Aim. To assess removal versus kill efficacies of antimicrobial treatments against thick biofilms with statistical confidence. Methods and results. A photo‐activated chlorine dioxide treatment (Photo ClO2) was tested in two ... -
Interactions of microorganisms within a urinary catheter polymicrobial biofilm model
(Wiley, 2022-09)Biofilms are often polymicrobial in nature, which can impact their behavior and overall structure, often resulting in an increase in biomass and enhanced antimicrobial resistance. Using plate counts and locked nucleic ... -
The impact of automated hand hygiene monitoring with and without complementary improvement strategies on performance rates
(Cambridge University Press, 2022-08)Objective: To determine how engagement of the hospital and/or vendor with performance improvement strategies combined with an automated hand hygiene monitoring system (AHHMS) influence hand hygiene (HH) performance rates. ... -
Efficacy of Common Antiseptic Solutions Against Clinically Relevant Planktonic Microorganisms
(SLACK, Inc., 2022-03)Prosthetic joint infections (PJIs) are among the most devastating complications after joint replacement. There is limited evidence regarding the efficacy of different antiseptic solutions in reducing planktonic microorganism ...
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