Scholarly Work - Center for Biofilm Engineering
Recent Submissions
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Efficacy of Common Antiseptic Solutions Against Clinically Relevant Planktonic Microorganisms
(SLACK, Inc., 2022-03)Prosthetic joint infections (PJIs) are among the most devastating complications after joint replacement. There is limited evidence regarding the efficacy of different antiseptic solutions in reducing planktonic microorganism ... -
Search for a Shared Genetic or Biochemical Basis for Biofilm Tolerance to Antibiotics across Bacterial Species
(American Society for Microbiology, 2022-04)Is there a universal genetically programmed defense providing tolerance to antibiotics when bacteria grow as biofilms? A comparison between biofilms of three different bacterial species by transcriptomic and metabolomic ... -
Antimicrobial Coating Efficacy for Prevention of Pseudomonas aeruginosa Biofilm Growth on ISS Water System Materials
(Frontiers Media SA, 2022-04)Biofilms can lead to biofouling, microbially induced corrosion, physical impediment and eventual loss in function of water systems, and other engineered systems. The remoteness and closed environment of the International ... -
Harvesting and Disaggregation: An Overlooked Step in Biofilm Methods Research
(MyJove Corporation, 2022-04)Biofilm methods consist of four distinct steps: growing the biofilm in a relevant model, treating the mature biofilm, harvesting the biofilm from the surface and disaggregating the clumps, and analyzing the sample. Of the ... -
Noninflammatory comedones have greater diversity in microbiome and are more prone to biofilm formation than inflammatory lesions of acne vulgaris
(Wiley, 2020-12)Background: The ability of C. acnes strains to form biofilms has been correlated with their virulence. Objective: This study examined biofilm and skin microbiota in acne patients in order to understand their role in the ... -
Isolation and Characterization of Lignocellulose-Degrading Geobacillus thermoleovorans from Yellowstone National Park
(American Society for Microbiology, 2022-05)The microbial degradation of lignocellulose in natural ecosystems presents numerous biotechnological opportunities, including biofuel production from agricultural waste and feedstock biomass. To explore the degradation ... -
The importance of understanding the infectious microenvironment
(Elsevier BV, 2022-03)Standard doses of antibiotics do not efficiently treat chronic infections of the soft tissue and bone. In this Personal View, we advocate for improving treatment of these infections by taking the infectious microenvironment ... -
Investigation of Raman Spectroscopic Signatures with Multivariate Statistics: An Approach for Cataloguing Microbial Biosignatures
(Mary Ann Liebert Inc, 2021-09)Spectroscopic instruments are increasingly being implemented in the search for extraterrestrial life. However, microstructural spectral analyses of alien environments could prove difficult without knowledge on the molecular ... -
Potential use of fungal-bacterial co-cultures for the removal of organic pollutants
(Informa UK Limited, 2021-07)Fungi and bacteria coexist in a wide variety of natural and artificial environments which can lead to their association and interaction – ranging from antagonism to cooperation – that can affect the survival, colonization, ... -
Screening of Additive Formulations Enables Off-Chip Drop Reverse Transcription Quantitative Polymerase Chain Reaction of Single Influenza A Virus Genomes
(American Chemical Society, 2021-03)The miniaturization of polymerase chain reaction (PCR) using drop-based microfluidics allows for amplification of single nucleic acids in aqueous picoliter-sized drops. Accurate data collection during PCR requires that ... -
Interlaboratory evaluations of a standardized quantitative test method for determining the bactericidal and tuberculocidal efficacy of antimicrobial substances on hard non-porous surfaces
(Elsevier BV, 2022-04)The development, validation, and use of new quantitative methodologies for testing the effectiveness of antimicrobial products are necessary to meet the regulatory challenges associated with an ever-changing marketplace, ... -
Ureolysis-induced calcium carbonate precipitation (UICP) in the presence of CO2-affected brine: A field demonstration
(Elsevier BV, 2021-07)Biomineralization is an emerging biotechnology for subsurface engineering applications like remediating leaky wellbores. The process relies on ureolysis to induce precipitation of calcium carbonate in undesired flow paths. ... -
Biofilms vs. cities and humans vs. aliens – a tale of reproducibility in biofilms
(Elsevier BV, 2021-06)In recent decades the scientific community has started to appreciate that most microorganisms live in complex 3D structures composed of cells, polysaccharides, and other components such as proteins, extracellular (e)DNA, ... -
A Novel Irrigant to Eliminate Planktonic Bacteria and Eradicate Biofilm Superstructure With Persistent Effect During Total Hip Arthroplasty
(Elsevier BV, 2022-02)Background Numerous studies have examined the use of topical and irrigation-related adjuvants to decrease the risk of periprosthetic joint infection (PJI) after total hip arthroplasty. Many issues related to their use ... -
Screening of Additive Formulations Enables Off-Chip Drop Reverse Transcription Quantitative Polymerase Chain Reaction of Single Influenza A Virus Genomes
(American Chemical Society, 2021-03)The miniaturization of polymerase chain reaction (PCR) using drop-based microfluidics allows for amplification of single nucleic acids in aqueous picoliter-sized drops. Accurate data collection during PCR requires that ... -
Answer Set Programming for Computing Constraints-Based Elementary Flux Modes: Application to Escherichia coli Core Metabolism
(MDPI AG, 2020-12)Elementary Flux Modes (EFMs) provide a rigorous basis to systematically characterize the steady state, cellular phenotypes, as well as metabolic network robustness and fragility. However, the number of EFMs typically grows ... -
An inexpensive, versatile, compact, programmable temperature controller and thermocycler for simultaneous analysis and visualization within a microscope
(Springer Science and Business Media LLC, 2021-05)Microfluidic Lab on a Chip (LOC) devices are key enabling technologies for research and industry due to their compact size, which increases the number of integrated operations while decreasing reagent use. Common operations ... -
Community-led, integrated, reproducible multi-omics with anvi’o
(Springer Science and Business Media LLC, 2020-12)Big data abound in microbiology, but the workflows designed to enable researchers to interpret data can constrain the biological questions that can be asked. Five years after anvi’o was first published, this community-led ... -
Role of hibernation promoting factor in ribosomal protein stability during Pseudomonas aeruginosa dormancy
(MDPI, 2020-12)Pseudomonas aeruginosa is an opportunistic pathogen that causes biofilm-associated infections. P. aeruginosa can survive in a dormant state with reduced metabolic activity in nutrient-limited environments, including the ... -
Subsurface hydrocarbon degradation strategies in low- and high-sulfate coal seam communities identified with activity-based metagenomics
(Springer Science and Business Media LLC, 2022-02)Environmentally relevant metagenomes and BONCAT-FACS derived translationally active metagenomes from Powder River Basin coal seams were investigated to elucidate potential genes and functional groups involved in hydrocarbon ...
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