Scholarly Work - Center for Biofilm Engineering
Recent Submissions
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Impact of an automated hand hygiene monitoring system and additional promotional activities on hand hygiene performance rates and healthcare-associated infections
(2019-07)Objective: Determine the impact of an automated hand hygiene monitoring system (AHHMS) plus complementary strategies on hand hygiene performance rates and healthcare-associated infections (HAIs). Design: Retrospective, ... -
A Novel Gastric Spheroid Co-culture Model Reveals Chemokine-Dependent Recruitment of Human Dendritic Cells to the Gastric Epithelium
(2019-03)Background & Aims Gastric dendritic cells (DCs) control the adaptive response to infection with Helicobacter pylori, a major risk factor for peptic ulcer disease and gastric cancer. We hypothesize that DC interactions ... -
Randomized controlled trial evaluating the antimicrobial efficacy of chlorhexidine gluconate and para-chloro-meta-xylenol handwash formulations in real-world doses
(2019-06)Chlorhexidine gluconate-based soaps have become the gold standard for handwashing in critical care settings and para-chloro-meta-xylenol is an effective alternative antibacterial active ingredient. This study benchmarked ... -
Who goes in and out of patient rooms? An observational study of room entries and exits in the acute care setting
(2019-05)The objective of this study is to determine what percentage of patient room entries and exits (opportunities) are attributed to health care personnel (HCP) and non-HCP. A total of 14,876 opportunities were observed by ... -
Kinetics of Calcite Precipitation by Ureolytic Bacteria under Aerobic and Anaerobic Conditions
(2019-05)The kinetics of urea hydrolysis (ureolysis) and induced calcium carbonate (CaCO3) precipitation for engineering use in the subsurface was investigated under aerobic conditions using Sporosarcina pasteurii (ATCC strain ... -
Quorum sensing inhibition as a promising method to control biofilm growth in metalworking fluids
(2019-04)Microbial contamination in metalworking systems is a critical problem. This study determined the microbial communities in metalworking fluids (MWFs) from two machining shops and investigated the effect of quorum sensing ... -
Dynamic processing of DOM: Insight from exometabolomics, fluorescence spectroscopy, and mass spectrometry
(2018-06)Dissolved organic matter (DOM) in freshwater environments is an important source of organic carbon, supporting bacterial respiration. Frozen environments cover vast expanses of our planet, with glaciers and ice-sheets ... -
Bacterial Adhesion and Biofilm Formation on Textured Breast Implant Shell Materials
(2019-04)"Background Bacterial biofilms have been implicated with breast implant complications including capsular contracture and anaplastic large-cell lymphoma. The actual mechanisms for either are still under active investigation ... -
Metagenomic Profiling of Microbial Pathogens in the Little Bighorn River, Montana
(2019-03)The Little Bighorn River is the primary source of water for water treatment plants serving the local Crow Agency population, and has special significance in the spiritual and ceremonial life of the Crow tribe. Unfortunately, ... -
Hypoxia arising from concerted oxygen consumption by neutrophils and microorganisms in biofilms
(2018-06)Infections associated with microbial biofilms are often found to involve hypoxic or anoxic conditions within the biofilm or its vicinity. To shed light on the phenomenon of local oxygen depletion, mathematical reaction-diffusion ... -
Cytoprotective Nrf2 pathway is induced in chronically txnrd 1-deficient hepatocytes
(2009-07)"Background Metabolically active cells require robust mechanisms to combat oxidative stress. The cytoplasmic thioredoxin reductase/thioredoxin (Txnrd1/Txn1) system maintains reduced protein dithiols and provides electrons ... -
A permeability-increasing drug synergizes with bacterial efflux pump inhibitors and restores susceptibility to antibiotics in multi-drug resistant Pseudomonas aeruginosa strains
(2019-03)Resistance to antibiotics poses a major global threat according to the World Health Organization. Restoring the activity of existing drugs is an attractive alternative to address this challenge. One of the most efficient ... -
Multiscale analysis of autotroph-heterotroph interactions in a high-temperature microbial community
(2018-09)Interactions among microbial community members can lead to emergent properties, such as enhanced productivity, stability, and robustness. Iron-oxide mats in acidic (pH 2–4), high-temperature (> 65 °C) springs of Yellowstone ... -
Changes in microbial communities and associated water and gas geochemistry across a sulfate gradient in coal beds: Powder River Basin, USA
(2019-01)Competition between microbial sulfate reduction and methanogenesis drives cycling of fossil carbon and generation of CH4 in sedimentary basins. However, little is understood about the fundamental relationship between ... -
α-Chymotrypsin Immobilized on a Low-Density Polyethylene Surface Successfully Weakens Escherichia coli Biofilm Formation
(2018-12)The protease α-chymotrypsin (α-CT) was covalently immobilized on a low-density polyethylene (LDPE) surface, providing a new non-leaching material (LDPE-α-CT) able to preserve surfaces from biofilm growth over a long working ... -
Current insights into the mechanisms and management of infection stones
(2018-11)Infection stones are complex aggregates of crystals amalgamated in an organic matrix that are strictly associated with urinary tract infections. The management of patients who form infection stones is challenging owing to ... -
Light-Based 3D Printing of Hydrogels with High-Resolution Channels
(2019-01)Hydrogels are soft, water-based gels with widespread applications in personal care products, medicine and biomedical engineering. Many applications require structuring the hydrogel into complex three-dimensional (3D) shapes. ... -
Field-scale modeling of microbially induced calcite precipitation
(2018-11)The biogeochemical process known as microbially induced calcite precipitation (MICP) is being investigated for engineering and material science applications. To model MICP process behavior in porous media, computational ... -
Non-destructive approaches for assessing biofouling of household reverse osmosis membranes
(2018-09)This study determined economic non-destructive methods to assess biofouling in point of use reverse osmosis (RO) membrane treatment systems. Three parallel household RO membrane units were operated under controlled feed ... -
Bacteriophage Cooperation Suppresses CRISPR-Cas3 and Cas9 Immunity
(2018-08)Bacteria utilize CRISPR-Cas adaptive immune systems for protection from bacteriophages (phages), and some phages produce anti-CRISPR (Acr) proteins that inhibit immune function. Despite thorough mechanistic and structural ...
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