Show simple item record

dc.contributor.authorStewart, Philip S.
dc.date.accessioned2015-12-09T22:42:30Z
dc.date.available2015-12-09T22:42:30Z
dc.date.issued2015-08
dc.identifier.citationStewart, Philip S.. "Prospects for Anti-Biofilm Pharmaceuticals." Pharmaceuticals 8 (August 2015): 504-511. DOI:https://dx.doi.org/10.3390/ph8030504.en_US
dc.identifier.issn1424-8247
dc.identifier.urihttps://scholarworks.montana.edu/xmlui/handle/1/9406
dc.description.abstractThis commentary highlights several avenues currently being pursued in research labs to the development of new anti-biofilm pharmaceuticals. There is a real need for alternative therapeutic modalities for treating the persistent infections that sometimes form on implanted medical devices or compromised niches within the body. Strategies being researched include discovering new antimicrobial agents that kill microorganisms in biofilms more effectively than do existing antibiotics, designing drugs that block microbial adhesion or interfere with intercellular communication, developing chemistries to disperse biofilms, and combining agents with different mechanisms of action. Though the need is great, the pathway to commercialization of new drugs is steep. One possible streamlined approach to navigating the regulatory approval process is to repurpose old drugs, a strategy that a few groups have shown can yield agents with anti-biofilm properties.en_US
dc.description.sponsorshipNIH/NIGMS award GM109452en_US
dc.rightsCC BY 4.0en_US
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/legalcodeen_US
dc.titleProspects for Anti-Biofilm Pharmaceuticalsen_US
dc.typeArticleen_US
mus.citation.extentfirstpage504en_US
mus.citation.extentlastpage511en_US
mus.citation.journaltitlePharmaceuticalsen_US
mus.citation.volume8en_US
mus.identifier.categoryChemical & Material Sciencesen_US
mus.identifier.categoryHealth & Medical Sciencesen_US
mus.identifier.doi10.3390/ph8030504en_US
mus.relation.collegeCollege of Engineeringen_US
mus.relation.departmentCenter for Biofilm Engineering.en_US
mus.relation.universityMontana State University - Bozemanen_US
mus.data.thumbpage1en_US
mus.contributor.orcidStewart, Philip S.|0000-0001-7773-8570en_US


Files in this item

Thumbnail

This item appears in the following Collection(s)

Show simple item record

CC BY 4.0
Except where otherwise noted, this item's license is described as CC BY 4.0