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dc.contributor.authorZhao, Ke
dc.contributor.authorPenttinen, Petri
dc.contributor.authorGuan, Tongwei
dc.contributor.authorXiao, Jing
dc.contributor.authorChen, Qiang
dc.contributor.authorXu, Jun
dc.contributor.authorLindström, Kristina
dc.contributor.authorZhang, Lili
dc.contributor.authorZhang, Xiaoping
dc.contributor.authorStrobel, Gary A.
dc.identifier.citationZhao, K., Penttinen, P., Guan, T., Xiao, J., Chen, Q., Xu, J., … Strobel, G. A. (2010). The Diversity and Anti-Microbial Activity of Endophytic Actinomycetes Isolated from Medicinal Plants in Panxi Plateau, China. Curr Microbiol, 62(1), 182–190. doi:10.1007/s00284-010-9685-3en_US
dc.description.abstractTraditional Chinese medicinal plants are sources of biologically active compounds, providing raw material for pharmaceutical, cosmetic and fragrance industries. The endophytes of medicinal plants participate in biochemical pathways and produce analogous or novel bioactive compounds. Panxi plateau in South-west Sichuan in China with its unique geographical and climatological characteristics is a habitat of a great variety of medicinal plants. In this study, 560 endophytic actinomycetes were isolated from 26 medicinal plant species in Panxi plateau. 60 isolates were selected for 16S rDNA-RFLP analysis and 14 representative strains were chosen for 16S rDNA sequencing. According to the phylogenetic analysis, seven isolates were Streptomyces sp., while the remainder belonged to genera Micromonospora, Oerskovia, Nonomuraea, Promicromonospora and Rhodococcus. Antimicrobial activity analysis combined with the results of amplifying genes coding for polyketide synthetase (PKS-I, PKS-II) and nonribosomal peptide synthetase (NRPS) showed that endophytic actinomycetes isolated from medicinal plants in Panxi plateau had broad-spectrum antimicrobial activity and potential natural product diversity, which further proved that endophytic actinomycetes are valuable reservoirs of novel bioactive compounds.en_US
dc.titleThe diversity and antimicrobial activity of endophytic actinomycetes isolated from medicinal plants in Panxi Plateau, Chinaen_US
mus.citation.journaltitleCurrent Microbiologyen_US
mus.identifier.categoryLife Sciences & Earth Sciencesen_US
mus.relation.collegeCollege of Agricultureen_US
mus.relation.departmentPlant Sciences & Plant Pathology.en_US
mus.relation.universityMontana State University - Bozemanen_US

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