Theses and Dissertations at Montana State University (MSU)
Permanent URI for this collectionhttps://scholarworks.montana.edu/handle/1/733
Browse
452 results
Search Results
Item Hydrodynamic analysis of human neutrophil N-formyl chemotactic receptor-G protein interactions : mapping of interfacial domains with receptor-mimetic peptides(Montana State University - Bozeman, College of Letters & Science, 1994) Bommakanti, Rajani KanthItem A total synthesis of dendrobine(Montana State University - Bozeman, College of Letters & Science, 1991) Lee, Cheol HaeItem Characterization of 1La and 1Lb emission from indole-polar solvent complexes by supersonic jet spectroscopy(Montana State University - Bozeman, College of Letters & Science, 1999) Short, Kurt WilliamItem Effects of anions on magnesium flame emission in flame photometry(Montana State University - Bozeman, College of Letters & Science, 1954) Anderson, Glen F.Item A study of the suspension effect observed in a Dowex-50 - water system(Montana State University - Bozeman, College of Letters & Science, 1961) Robbins, John EdwardItem Hyperthermal reactions of O(p3sP) with hydrogen and methane(Montana State University - Bozeman, College of Letters & Science, 2004) Garton, Donna Joan; Chairperson, Graduate Committee: Lee SpanglerHyperthermal reactions of O(3P) occur at the surfaces and in the exhaust gases of spacecraft that travel through the residual atmosphere of the Earth at high altitudes (200-600 km). These reactions may degrade materials through oxidation and erosion, or they may yield internally excited reaction products which emit radiation and contribute to the “signature” of a rocket plume. Crossed-beams experiments were used to study model reactions of O(3P) with H2, D2, CH4, and CD4 at center-of-mass collision energies in the range 8-75 kcal mol^-1. Interpretation of the experimental results has been strengthened by theoretical calculations carried out by collaborators. A study of the OH scattered flux as a function of collision energy has led to the determination of an experimental excitation function in the threshold region for the O(3P)+H2 → OH+H reaction. The experimental excitation function clearly matched the theoretical prediction, which confirmed that the laser-detonation source produces O(3P) atoms. The excitation function for the O(3P) + H2 reaction and the dynamics of the O(3P) + D2 reaction, observed experimentally for the first time, demonstrate that these reactions proceed mainly on triplet potential energy surfaces, with little or no intersystem crossing. Experiments on the reactions of O(3P) with methane have revealed a previously unobserved reaction pathway, which involves H-atom elimination: O(3P) + CH4 → OCH3 + H. The excitation function for this reaction has been measured, and the reaction barrier has been determined to be ∼46 kcal mol^-1. In addition, the expected H-atom abstraction reaction, O(3P) + CH4 → CH3 + OH, has been observed, and the dynamics have been investigated. Theoretical calculations identify a triplet-singlet curve crossing below the triplet barrier for the H-atom elimination reaction, but the observed dynamics indicate reaction exclusively on the two lowest-lying triplet surfaces. While it remains to be seen whether intersystem crossing will affect the outcome of other reactions involving hyperthermal atomic oxygen, unknown reactions which have high barriers are likely to be common in extreme environments such as low-Earth orbit, where spacecraft surfaces and exhaust gases suffer high-energy collisions with ambient atomic oxygen.Item Some aspects of the oxidation of delta-3-carene, 3, 7, 7-trimethyl bicyclo- (4.1.0) hept-3-ene(Montana State University - Bozeman, College of Letters & Science, 1975) Lai, Ching-EItem Mechanistic studies on the chemical oxidation of substituted tetrahydrobenzofurans(Montana State University - Bozeman, College of Letters & Science, 1985) Manfredi, Kirk PaulItem Studies towards the synthesis of the C(8)-C(15) fragment of tedanolide(Montana State University - Bozeman, College of Letters & Science, 2004) Cole, David James; Chairperson, Graduate Committee: Paul A. GriecoTedanolide is a 18-membered macrolide of marine origin which displays antitumor activity and presents a synthetic challenge. To date, the total synthesis of tedanolide has not been reported however the synthesis of 13-deoxytedanolide, another closely related macrolide isolated from a different sea sponge, was recently accomplished. Progress towards the synthesis of tedanolide is described with specific attention given to the synthesis of the C(8)-C(15) portion of the molecule. The approach involves the use of rigid bicyclic ring systems to control the stereocenters found in the natural product. The approach contained herein has not yet led to the total synthesis of tedanolide but has led to a precursor of the 18-membered ring.Item Metabolic fate and toxic effects of one of the components of Tetradymia glabrata(Montana State University - Bozeman, College of Letters & Science, 1975) Holian, Sandra Keller