Undergraduate Scholars Program

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The Undergraduate Scholars Program (USP) is one of the largest multidisciplinary undergraduate research programs at MSU. We are here to help undergraduate students in all disciplines pursue research, scholarship, and creative projects.



The Undergraduate Scholars Program (USP) facilitates, supports, and promotes undergraduate research and scholarship by providing funding and logistical support directly to students.

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Author: search.filters.author.Bernhard, Samuelsearch.filters.applied.f.department: search.filters.department.Chemistry & Biochemistry.

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    Analysis of GAL3 and Lactose functionalized PAMAM Binding by EPR
    (2013-03) Bernhard, Samuel; Cloninger, Mary
    In order to better understand the binding characteristics between lactose functionalized PAMAM dendrimers and the galactoside lectin Galectin-3, the synthetic production of heterogeneously functionalized TEMPO and Lactose PAMAM dendrimers were undertaken. To analyze the relevant lectin/ carbohydrate relationship, these dendrimers will be subjected to electron pair repulsion (EPR) studies. The implication of analyzing several dendrimer generations through EPR is that a quantitative understanding of the relationship between dendrimer size/ degree of functionalization and binding strength can be determined. In terms of progress, a significant portion of the synthesis has been completed. Optimized yields have been determined and characterization has been completed on the reactions that lead to the production of the Lactose tether.
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