Blood glucose/lactate responses from ingesting high fructose corn syrup and sucrose beverages

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Fructose has been the focus of many researchers. High fructose corn syrup has replaced sucrose in food products and has gained notoriety concerning possible negative effects on metabolism. Purpose: To examine whether a HFCS beverage alters glucose and lactate responses compared to a sucrose beverage. METHODS: Seven (3 male, 4 female: Mean±SD; 23.7±2.4yrs, 71.5±16.2kg, 173.9±9.6cm) adults volunteered. Subjects participated in two experimental trials after a 12 hour fast. A 10% beverage sweetened with HFCS or sucrose (30 g/300mL) was ingested. Blood samples were taken at -5, 30, 60, 90 and 120 minutes, coagulated for 20 minutes and centrifuged for 10 minutes. An ANOVA with repeated measures was used for statistical analysis. T-tests were used to differentiate means with Bonferroni adjustment (alpha level < 0.05). RESULTS: No interaction effect was observed between time and treatments. No treatment main effect was found for glucose (Means±SD: sucrose 4.0±0.92 mM/L; HFCS 4.28±1.06mM/L) or lactate (Mean±SD: sucrose 2.10±0.67mM/L; HFCS 2.15±0.68mMol/L). There was a significant time effect within blood glucose levels. Mean glucose concentration at 30 minutes was increased over baseline (Mean±SD: 5.6±0.98mM/L), and 60, 90, and 120 minutes. CONCLUSIONS: Glucose and lactate responses were not different from one another after ingestion of HFCS and sucrose.


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