Browsing by Author "Kordick, L.K."

Now showing 1 - 2 of 2

Basal, diurnal, and acute inflammation in normal versus overweight men.
(Lippincott Williams & Wilkins, 2012-12) Miles, Mary; Keller, J.M.; Kordick, L.K.; Kidd, J.R.
Increased inflammation is present in obese compared with normal weight individuals, but inflammation characteristics of nonobese, overweight individuals are less clear. Purpose: The objective of this study was to determine whether basal, circadian, and posteccentric exercise inflammation levels differ between normal and overweight men. Methods: Men (18–35 yr old) classified as normal weight (body mass index ≤2 5 kg·m-2, n = 20) and overweight (body mass index = 25–30 kg·m-2 conditions in random order. Maximal voluntary effort and eccentric actions (3 X 15) using the elbow flexor muscles of one arm were performed, and blood was collected preexercise and 4, 8, 12, and 24 h postexercise at 7:00 a.m., 12:00 p.m., 4:00 p.m., 8:00 p.m., and 7:00 a.m. Blood was collected on a time-matched schedule without exercise for CON. Soluble tumor necrosis factor receptor-1, interleukin-6, C-reactive protein (CRP), and cortisol responses (EX value j time-matched CON value) were measured. Results: Basal CRP was higher in the overweight compared with normal weight group (mean ± SD, 0.542 ± 0.578 vs 1.395 ± 1.041 mg·L-1). Soluble tumor necrosis factor receptor-1 increased (P < 0.05) 8 h postexercise in both groups, and the response was greater 12 and 24 h postexercise in the overweight compared with normal weight groups. Interleukin-6 increased (P < 0.05) 8 h postexercise, with a trend (P = 0.09) to be greater in the overweight group. CRP and cortisol responses were not detected. Conclusions: The low-grade inflammation state in overweight compared with normal weight men includes both higher basal CRP concentrations and enhanced acute inflammation, but not in changes to the circadian patterns of cortisol and inflammation variables.
Dietary, Anthropometric, Blood Lipid, and Performance Patterns of College Football Players During 8 Weeks of Training
(Human Kinetics, 2012) Miles, Mary; Kirwan, Rochelle D.; Kordick, L.K.; McFarland, S.; Lancaster, D.; Clark, K.
The purpose of this study was to determine the dietary, anthropometric, blood-lipid, and performance patterns of university-level American football players attempting to increase body mass during 8 wk of training. Methods: Three-day diet records, body composition (DEXA scan), blood lipids, and performance measures were collected in redshirt football players (N = 15, age 18.5 ± 0.6 yr) early season and after 8 wk of in-season training. Results: There was an increase (p < .05) from early-season to postseason testing for reported energy (+45%), carbohydrate (+82%), and protein (+29%) intakes and no change in the intake of fat. Fat intake was 41% of energy at the early-season test and 32% of energy at the postseason test. Increases (p < .05 for all) in performance measures, lean mass (70.5 ± 7.7–71.8 ± 7.7 kg), fat mass (15.9 ± 6.2–17.3 ± 6.8 kg), plasma total cholesterol (193.5 ± 32.4–222.6 ± 40.0 mg/dl), and low-density lipoproteins (LDL; 92.7 ± 32.7–124.5 ± 34.7 mg/dl) were measured. No changes were measured in triglycerides, very-low-density lipoproteins, or high-density lipoproteins. Conclusion: Increases in strength, power, speed, total body mass, muscle mass, and fat mass were measured. Cholesterol and LDL levels increased during the study to levels associated with higher risk for cardiovascular disease. It is possible that this is a temporary phenomenon, but it is cause for concern and an indication that dietary education to promote weight gain in a manner less likely to adversely affect the lipid profile is warranted.