Browsing by Author "Nurkenov, O. A."
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Item Synthesis and Biological Activity of Hydrazones of o- and p-Hydroxybenzoic Acids. Spatial Structure of 5-Bromo-2-hydroxybenzylidene-4-hydroxybenzohydrazide(2017-10) Nurkenov, O. A.; Satpaeva, Zh. B.; Schepetkin, Igor A.; Khlebnikov, Andrei I.; Turdybekov, K. M.; Seilkhanov, T. M.; Fazylov, S. D.A series of hydrazones based on hydrazides of o- and p-hydroxybenzoic acids have been prepared. N-(5-Bromo-2-hydroxybenzylidene)-4-hydroxybenzohydrazide has been studied by X-ray diffraction analysis; its molecule forms hydrogen bond with a solvating ethanol molecule. Biological activity of the synthesized hydrazones towards cathepsin E and(or) elastase of human neutrophils has been determined.