Theses and Dissertations at Montana State University (MSU)
Permanent URI for this collectionhttps://scholarworks.montana.edu/handle/1/733
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Item Influence of alpha intrusion during sleep: psychological and physiological implications(Montana State University - Bozeman, College of Letters & Science, 2022) Greenlund, Ian Mark; Chairperson, Graduate Committee: Jason CarterPoor sleep quality is pervasive in developed societies from chronic sleep disturbances or self-imposed sleep curtailment. Sleep disorders like insomnia are associated with regular sleep difficulties including sleep initiation and maintenance. Anxiety and depression exhibit a bidirectional relationship with insomnia, potentially exacerbating poor sleep quality and altering sleep microarchitecture via high frequency electroencephalographic (EEG) intrusion. This includes wake EEG alpha and beta rhythms. An association between high frequency intrusion and psychological dysfunction is present, but little is known regarding alpha and beta frequency intrusion 1) presence with state and trait anxiety symptoms, 2) impact on nocturnal blood pressure regulation, and 3) exacerbation with binge alcohol consumption. In study 1, we examined the relationship between state and trait anxiety severity with alpha and beta intrusion during stage N2 sleep, slow wave sleep (SWS), and rapid eye movement (REM) sleep in 32 participants. We demonstrated that alpha and beta frequency intrusion was augmented in participants with higher state, but not trait anxiety. In study 2, we investigated whether alpha and beta frequency intrusion impacted nocturnal blood pressure regulation in 36 young, healthy adults. Overall, systolic arterial pressure (SAP) dipping and cardiovagal baroreflex sensitivity (cvBRS) were not related alpha and beta spectral power during sleep. In study 3, we explored whether binge alcohol consumption could further exacerbate alpha and beta intrusion during sleep in higher state and trait anxiety participants in 31 participants. A secondary aim of this study was to determine if high frequency spectral power was different between sexes following alcohol consumption. Following laboratory familiarization night (study 2), participants were tested twice, ~1 month apart in a randomized, crossover design consuming either an alcohol dose (study 3) based upon biological sex and body weight, or fluid control beverage (study 1) two hours prior to lights out. Alpha and beta spectral power was not different between lower and higher state and trait anxiety, but was augmented in females compared to age-matched males. Collectively, these studies are the first investigate alpha intrusion presence with state and trait anxiety symptoms, impact on nocturnal blood pressure regulation, and sex specific exacerbation following alcohol consumption.