Spatial working memory alters the efficacy of input to visual cortex

dc.contributor.authorMerrikhi, Yaser
dc.contributor.authorClark, Kelsey
dc.contributor.authorAlbarran, Eddy
dc.contributor.authorParsa, Mohammadbagher
dc.contributor.authorZirnsak, Marc
dc.contributor.authorMoore, Tirin
dc.contributor.authorNoudoost, Behrad
dc.date.accessioned2017-08-27T01:39:29Z
dc.date.available2017-08-27T01:39:29Z
dc.date.issued2017-04
dc.description.abstractPrefrontal cortex modulates sensory signals in extrastriate visual cortex, in part via its direct projections from the frontal eye field (FEF), an area involved in selective attention. We find that working memory-related activity is a dominant signal within FEF input to visual cortex. Although this signal alone does not evoke spiking responses in areas V4 and MT during memory, the gain of visual responses in these areas increases, and neuronal receptive fields expand and shift towards the remembered location, improving the stimulus representation by neuronal populations. These results provide a basis for enhancing the representation of working memory targets and implicate persistent FEF activity as a basis for the interdependence of working memory and selective attention.en_US
dc.description.sponsorshipNational Institutes of Health (R01EY014924, R01EY026924); National Science Foundation (143221, 1632738)en_US
dc.identifier.citationMerrikhi, Yaser, Kelsey Clark, Eddy Albarran, Mohammadbagher Parsa, Marc Zirnsak, Tirin Moore, and Behrad Noudoost. "Spatial working memory alters the efficacy of input to visual cortex." Nature Communications 8 (April 2017). DOI: 10.1038/ncomms15041.en_US
dc.identifier.issn2041-1723
dc.identifier.urihttps://scholarworks.montana.edu/handle/1/13589
dc.rightsCC-BY 4.0en_US
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/legalcodeen_US
dc.titleSpatial working memory alters the efficacy of input to visual cortexen_US
dc.typeArticleen_US
mus.citation.extentfirstpage15041en_US
mus.citation.journaltitleNature Communicationsen_US
mus.citation.volume8en_US
mus.data.thumbpage3en_US
mus.identifier.categoryEngineering & Computer Scienceen_US
mus.identifier.categoryLife Sciences & Earth Sciencesen_US
mus.identifier.doi10.1038/ncomms15041en_US
mus.relation.collegeCollege of Agricultureen_US
mus.relation.departmentMicrobiology & Cell Biology.en_US
mus.relation.departmentComputer Science.en_US
mus.relation.universityMontana State University - Bozemanen_US

Files

Original bundle
Now showing 1 - 1 of 1
Loading...
Thumbnail Image
Name:
Merrikhi_NComms_2017.pdf
Size:
1.6 MB
Format:
Adobe Portable Document Format
Description:
Spatial working memory alters the efficacy of input to visual cortex (PDF)
License bundle
Now showing 1 - 1 of 1
No Thumbnail Available
Name:
license.txt
Size:
826 B
Format:
Item-specific license agreed upon to submission
Description:
Copyright (c) 2002-2022, LYRASIS. All rights reserved.