The history and market impact of CRISPR RNA-guided nucleases

dc.contributor.authorvan Erp, Paul B. G.
dc.contributor.authorBloomer, Gary
dc.contributor.authorWilkinson, Royce A.
dc.contributor.authorWiedenheft, Blake A.
dc.date.accessioned2016-05-26T13:55:06Z
dc.date.available2016-05-26T13:55:06Z
dc.date.issued2015-06
dc.description.abstractThe interface between viruses and their hosts’ are hot spots for biological and biotechnological innovation. Bacteria use restriction endonucleases to destroy invading DNA, and industry has exploited these enzymes for molecular cut-and-paste reactions that are central to many recombinant DNA technologies. Today, another class of nucleases central to adaptive immune systems that protect bacteria and archaea from invading viruses and plasmids are blazing a similar path from basic science to profound biomedical and industrial applications.en_US
dc.description.sponsorshipNational Institutes of Health (P20GM103500 and R01GM108888), the National Science Foundation EPSCoR (EPS-110134), the M.J. Murdock Charitable Trust, and the Montana State University Agricultural Experimental Stationen_US
dc.identifier.citationVan Erp, Paul BG, Gary Bloomer, Royce Wilkinson, and Blake Wiedenheft. “The History and Market Impact of CRISPR RNA-Guided Nucleases.” Current Opinion in Virology 12 (June 2015): 85–90. doi:10.1016/j.coviro.2015.03.011.en_US
dc.identifier.issn1879-6257
dc.identifier.urihttps://scholarworks.montana.edu/handle/1/9879
dc.rightsYou are free to: Share — copy and redistribute the material in any medium or format Adapt — remix, transform, and build upon the material for any purpose, even commercially. The licensor cannot revoke these freedoms as long as you follow the license terms. Under the following terms: Attribution — You must give appropriate credit, provide a link to the license, and indicate if changes were made. You may do so in any reasonable manner, but not in any way that suggests the licensor endorses you or your use. No additional restrictions — You may not apply legal terms or technological measures that legally restrict others from doing anything the license permits.en_US
dc.rights.urihttp://creativecommons.org/licenses/by/4.0/legalcodeen_US
dc.titleThe history and market impact of CRISPR RNA-guided nucleasesen_US
dc.typeArticleen_US
mus.citation.extentfirstpage85en_US
mus.citation.extentlastpage90en_US
mus.citation.journaltitleCurrent opinion in virologyen_US
mus.citation.volume12en_US
mus.data.thumbpage3en_US
mus.identifier.categoryLife Sciences & Earth Sciencesen_US
mus.identifier.doi10.1016/j.coviro.2015.03.011en_US
mus.relation.collegeCollege of Agricultureen_US
mus.relation.collegeCollege of Letters & Scienceen_US
mus.relation.departmentMicrobiology & Immunology.en_US
mus.relation.universityMontana State University - Bozemanen_US

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