The application of biofilm science to the study and control of bacterial infections

Date
2003-11Author
Costerton, J. William
Veeh, Richard Harold
Shirtliff, Mark E.
Pasmore, M.
Post, C.
Ehrlich, Garth D.
Metadata
Show full item recordAbstract
Unequivocal direct observations have established that the bacteria that cause device-related and other chronic infections grow in matrix-enclosed biofilms. The diagnostic and therapeutic strategies that have served us so well in the partial eradication of acute epidemic bacterial diseases have not yielded accurate data or favorable outcomes when applied to these biofilm diseases. We discuss the potential benefits of the application of the new methods and concepts developed by biofilm science and engineering to the clinical management of infectious diseases.
Citation
Costerton, William, Richard Veeh, Mark Shirtliff, Mark Pasmore, Christopher Post, and Garth Ehrlich. “The Application of Biofilm Science to the Study and Control of Chronic Bacterial Infections.” J. Clin. Invest. 112, no. 10 (November 15, 2003): 1466–1477. doi:10.1172/jci200320365.