Multi-curvature micropatterns unveil distinct calcium and mitochondrial dynamics in neuronal networks

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2021-01

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Royal Society of Chemistry

Abstract

Soft-embossed highly-parallelized multi-curvature micropatterns model the impact of different curvatures (k = 0.003–0.2 μm−1) inspired by the human cerebral tissue folds on changes in spontaneous neuronal calcium signals and mitochondrial transport.

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curvature micropatterns calcium neuronal networks dynamics

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Khan, H., Beck, C., & Kunze, A. (2021). Multi-curvature micropatterns unveil distinct calcium and mitochondrial dynamics in neuronal networks. Lab on a Chip, 21(6), 1164-1174.

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