Resident bacterial flora in the skin of C57BL/6 mice housed under SPF conditions

dc.contributor.authorTavakkol, Zarry
dc.contributor.authorSamuelson, Derrick
dc.contributor.authorPulcini, Elinor D.
dc.contributor.authorUnderwood, Robert A.
dc.contributor.authorUsui, Marcia L.
dc.contributor.authorCosterton, J. William
dc.contributor.authorJames, Garth A.
dc.contributor.authorOlerud, John E.
dc.contributor.authorFleckman, Philip
dc.date.accessioned2017-04-10T20:00:05Z
dc.date.available2017-04-10T20:00:05Z
dc.date.issued2010-09
dc.description.abstractResearch in cutaneous biology frequently involves models that use mice housed in SPF conditions. Little information is available concerning the species of bacteria that normally inhabit the skin of these mice. The aim of this study was to characterize the bacterial skin flora of mice housed under SPF conditions. Skin biopsies from C57BL/6 mice under normal and surgically prepped conditions were both cultured and analyzed by using DNA extraction and sequencing. The species isolated most commonly from culture were staphylococci. Coagulase-negative staphylococci were isolated more frequently than was Staphylococcus aureus. Molecular sequencing yielded several additional organisms not found by culture. Overall, culturing of isolates yielded 14 species of bacteria, and molecular sequencing identified another 6 species. Investigators conducting cutaneous research in mouse models should aware of the cutaneous bacterial flora present on these mice.en_US
dc.identifier.citationTavakkol Z, Samuelson D, Pulcini ED, Underwood RA, Usui ML, Costerton WJ, James GA, Olerud JE, Fleckman P, "Resident bacterial flora in the skin of C57BL/6 mice housed under SPF conditions," Journal of the American Association for Laboratory Animal Science, September 2010; 49(5): 1-4.en_US
dc.identifier.issn1559-6109
dc.identifier.urihttps://scholarworks.montana.edu/handle/1/12686
dc.titleResident bacterial flora in the skin of C57BL/6 mice housed under SPF conditionsen_US
dc.typeArticleen_US
mus.citation.extentfirstpage588en_US
mus.citation.extentlastpage591en_US
mus.citation.issue5en_US
mus.citation.journaltitleJournal of the American Association for Laboratory Animal Scienceen_US
mus.citation.volume49en_US
mus.data.thumbpage2en_US
mus.identifier.categoryChemical & Material Sciencesen_US
mus.identifier.categoryEngineering & Computer Scienceen_US
mus.identifier.categoryLife Sciences & Earth Sciencesen_US
mus.relation.collegeCollege of Agricultureen_US
mus.relation.collegeCollege of Engineeringen_US
mus.relation.collegeCollege of Letters & Scienceen_US
mus.relation.departmentChemical & Biological Engineering.en_US
mus.relation.departmentChemical Engineering.en_US
mus.relation.departmentChemistry & Biochemistry.en_US
mus.relation.departmentMicrobiology & Immunology.en_US
mus.relation.researchgroupCenter for Biofilm Engineering.en_US
mus.relation.universityMontana State University - Bozemanen_US

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