Molecular imaging and depth profiling of biomaterials interfaces by femtosecond laser desorption postionization mass spectrometry

dc.contributor.authorCui, Y.
dc.contributor.authorBhardwaj, C.
dc.contributor.authorMilasinovic, S.
dc.contributor.authorCarlson, Ross P.
dc.contributor.authorGordon, R. J.
dc.contributor.authorHanley, L.
dc.date.accessioned2017-01-24T17:45:13Z
dc.date.available2017-01-24T17:45:13Z
dc.date.issued2013-10
dc.description.abstractMass spectrometry (MS) imaging is increasingly being applied to probe the interfaces of biomaterials with invasive microbial biofilms, human tissue, or other biological materials. Laser desorption vacuum ultraviolet postionization with 75 fs, 800 nm laser pulses (fs-LDPI-MS) was used to collect MS images of a yeast–Escherichia coli co-culture biofilm. The method was also used to depth profile a three-dimensionally structured, multispecies biofilm. Finally, fs-LDPI-MS analyses of yeast biofilms grown under different conditions were compared with LDPI-MS using ultraviolet, nanosecond pulse length laser desorption as well as with fs laser desorption ionization without postionization. Preliminary implications for the use of fs-LDPI-MS for the analysis of biomaterials interfaces are discussed and contrasted with established methods in MS imaging.en_US
dc.identifier.citationCui Y, Bhardwaj C, Milasinovic S, Carlson RP, Gordon RJ, Hanley L, "Molecular imaging and depth profiling of biomaterials interfaces by femtosecond laser desorption postionization mass spectrometry," ACS Applied Materials & Interfaces October 2013, 5 (19):9269–9275.en_US
dc.identifier.issn1944-8244
dc.identifier.urihttps://scholarworks.montana.edu/handle/1/12425
dc.titleMolecular imaging and depth profiling of biomaterials interfaces by femtosecond laser desorption postionization mass spectrometryen_US
dc.typeArticleen_US
mus.citation.extentfirstpage9269en_US
mus.citation.extentlastpage9275en_US
mus.citation.issue19en_US
mus.citation.journaltitleACS Applied Materials & Interfacesen_US
mus.citation.volume5en_US
mus.data.thumbpage5en_US
mus.identifier.categoryEngineering & Computer Scienceen_US
mus.identifier.categoryLife Sciences & Earth Sciencesen_US
mus.identifier.doi10.1021/am4020633en_US
mus.relation.collegeCollege of Agricultureen_US
mus.relation.collegeCollege of Engineeringen_US
mus.relation.collegeCollege of Letters & Scienceen_US
mus.relation.departmentCell Biology & Neuroscience.en_US
mus.relation.departmentCenter for Biofilm Engineering.en_US
mus.relation.departmentElectrical & Computer Engineering.en_US
mus.relation.departmentMicrobiology & Immunology.en_US
mus.relation.researchgroupCenter for Biofilm Engineering.en_US
mus.relation.universityMontana State University - Bozemanen_US

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