Solvent coordination to palladium can invert the selectivity of oxidative addition

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Date

2022-01

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Royal Society of Chemistry

Abstract

In the presence of the bulky monophosphine PtBu3, palladium usually prefers to react with Ar–Cl over Ar–OTf bonds. However, strongly coordinating solvents can bind to palladium, inducing a reversal of selectivity.

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Keywords

solvent coordination, palladium, oxidative addition

Citation

Elias, E. K., Rehbein, S. M., & Neufeldt, S. R. (2022). Solvent coordination to palladium can invert the selectivity of oxidative addition. Chemical science, 13(6), 1618-1628.

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